Titlebook: Circadian Pharmacokinetics; Baojian Wu,Danyi Lu,Dong Dong Book 2020 The Editor(s) (if applicable) and The Author(s), under exclusive licen

BROW

周興旺

Missile

Circadian Clock and CYP Metabolism,t the circadian clock by modulating melatonin metabolism, glucocorticoid, and NAPDH synthesis. This chapter provides an overview of current understanding of how the circadian clock regulates the expression and activities of CYP enzymes to affect xenobiotic detoxification and lipid metabolism, and how CYP activities affect circadian rhythms.

結(jié)合

RLS898

榮幸

大氣層

Circadian Clock and Metabolic Diseases,ays a significant role in the occurrence and development of metabolic diseases. Circadian rhythms generated by central and peripheral clocks are involved in maintaining metabolic homeostasis. Disruption of the circadian rhythms is an established risk factor for metabolic dysfunction and results in m

Conscientious

etiquette

Circadian Clock and Non-CYP Phase I Metabolism,lock on non-CYP phase I metabolism are highlighted recently in mice lacking the clock gene ., . or .. .-deficient mice show altered expression of non-CYP phase I enzymes and blunted rhythms in enzyme expression. In addition, circadian expressions of non-CYP phase I enzymes (e.g., FMO5) are associate

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