Titlebook: Circadian Pharmacokinetics; Baojian Wu,Danyi Lu,Dong Dong Book 2020 The Editor(s) (if applicable) and The Author(s), under exclusive licen

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書目名稱Circadian Pharmacokinetics影響因子(影響力)




書目名稱Circadian Pharmacokinetics影響因子(影響力)學科排名




書目名稱Circadian Pharmacokinetics網(wǎng)絡(luò)公開度




書目名稱Circadian Pharmacokinetics網(wǎng)絡(luò)公開度學科排名




書目名稱Circadian Pharmacokinetics被引頻次




書目名稱Circadian Pharmacokinetics被引頻次學科排名




書目名稱Circadian Pharmacokinetics年度引用




書目名稱Circadian Pharmacokinetics年度引用學科排名




書目名稱Circadian Pharmacokinetics讀者反饋




書目名稱Circadian Pharmacokinetics讀者反饋學科排名

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ers are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.978-981-15-8809-9978-981-15-8807-5

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Anonymous

Lay James Gibson,James B. Nelsondependent drug pharmacokinetics and therapeutic outcomes. In this chapter, we update current knowledge on uptake transporters that contribute significantly to drug transport and pharmacokinetics. Particularly, regulation of uptake transporters by circadian clock and the underlying mechanisms are covered.

Anonymous

Tatsuhiko Kawashima,Iwan Azis,Michael Taned with dosing time-dependency in pharmacokinetics and drug effects. In this chapter, we review circadian regulation of efflux transporters and its influences on drug disposition, toxicity, and efficacy.

混雜人

Tatsuhiko Kawashima,Iwan Azis,Michael Tane-dependent drug effects is highly relevant for chronotherapeutics. In this chapter, we perform a review on the influences of circadian rhythms on drug pharmacokinetics in both humans and experimental animals. We also discuss the role of pharmacokinetics in chronotherapeutics.

Obligatory

Introduction to Mammalian Circadian Clock System,iseases present circadian rhythms in flares of symptoms. Thus, it is of great interest to investigate circadian rhythms in depth, which would help to find means to combat diseases and to optimize drug treatment. In this chapter, we introduce mammalian circadian clock system and discuss the role of circadian clock in human health.

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