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Titlebook: Biological Reactive Intermediates V; Basic Mechanistic Re Robert Snyder,I. Glenn Sipes,Charlotte M. Witmer Book 1996 The Editor(s) (if appl

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41#
發(fā)表于 2025-3-28 16:50:10 | 只看該作者
Pathologie und Klink in EinzeldarstellungenThe quinolone antibiotic BAY y 3118 is a photochemically labile compound, and irradiation with UV-A light leads to its rapid decomposition. In vivo, following oral drug administration to guinea pigs, irradiation of the animals not only results in a severe local phototoxicity, but also leads to systemic phototoxic reactions [1].
42#
發(fā)表于 2025-3-28 19:44:30 | 只看該作者
Studies on the Mechanism of Phototoxicity of BAY y 3118 and Other QuinolonesThe quinolone antibiotic BAY y 3118 is a photochemically labile compound, and irradiation with UV-A light leads to its rapid decomposition. In vivo, following oral drug administration to guinea pigs, irradiation of the animals not only results in a severe local phototoxicity, but also leads to systemic phototoxic reactions [1].
43#
發(fā)表于 2025-3-29 02:32:13 | 只看該作者
Biological Reactive Intermediates V978-1-4757-9480-9Series ISSN 0065-2598 Series E-ISSN 2214-8019
44#
發(fā)表于 2025-3-29 03:18:36 | 只看該作者
https://doi.org/10.1007/978-3-662-34539-9aloyloxymethyl dopa ester (Binderup et al. 1971, Wickers et al. 1985). These pro-drugs administrated to rat and monkey undergo an hydrolysis releasing free PIV, which is excreted in urine mostly unchanged or as carnitine or glucuronic acid conjugates.
45#
發(fā)表于 2025-3-29 10:02:26 | 只看該作者
Definition, Klassifikation und Nomenklatur,r- and intracellular signal transduction. Ca./calmodulin are involved in the activation process of the ROI-generating system. A rise of intracellular Ca. is necessary, but not sufficient to trigger the release of ROIs. As a second signal, protein phosphorylation seems to be involved in the activation process.
46#
發(fā)表于 2025-3-29 15:23:27 | 只看該作者
https://doi.org/10.1007/978-1-4757-9480-9Oxidation; biochemistry; cytochrome P450; dopamine; enzymes; metabolism; neurotoxicity; proteins
47#
發(fā)表于 2025-3-29 17:01:02 | 只看該作者
978-1-4757-9482-3The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
48#
發(fā)表于 2025-3-29 22:05:08 | 只看該作者
49#
發(fā)表于 2025-3-30 03:17:54 | 只看該作者
50#
發(fā)表于 2025-3-30 04:07:03 | 只看該作者
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