Titlebook: Biological Reactive Intermediates V; Basic Mechanistic Re Robert Snyder,I. Glenn Sipes,Charlotte M. Witmer Book 1996 The Editor(s) (if appl

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Muskelrelaxation bei alten Menschen,uction via the serum response element SRE in the c-. promoter. Their activation leads to a rapid induction of c-. gene expression. Activation of mitogen-activated protein kinases (MAPK) by signalling cascades and subsequent TCF phosphorylation are known to be essential steps in this transcriptional

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https://doi.org/10.1007/978-3-662-34539-9d bradykinesia. Pathologically, the hallmark of Parkinson’s disease is the progressive degeneration of the dopamine (DA)-containing neurons of the nigrostriatal projection. Neurological deficits associated with the loss of DA neurons do not appear until the degeneration is extensive, presumably due

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Klinik der gyn?kologischen R?ntgentherapiegnificant environmental contaminants (Hawley, 1971; US-EPA, 1985). It has been shown that biotransformation is necessary to exhibit toxicity (Brodie et al., 1971). Both 1,2-dichlorobenzene and its 1,4-isomer are metabolized by cytochrome P450 enzymes to an epoxide intermediate. This epoxide may eith

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,Die Anwendung der R?ntgenstrahlen am Ovar, allograft rejection. However, its metabolism by the cytochrome P450 mixed-function oxidase (MFO) system frequently results in hepatotoxicity as seen by jaundice and altered serum enzyme in hepatic transplant recipients, hyperbilirubinemia, hypoproteinemia, and albuminemia in rats (Whiting et al., 1

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Selective Depletion of Mitochondrial Glutathione Content by Pivalic Acid and Valproic Acid in Rat Lialoyloxymethyl dopa ester (Binderup et al. 1971, Wickers et al. 1985). These pro-drugs administrated to rat and monkey undergo an hydrolysis releasing free PIV, which is excreted in urine mostly unchanged or as carnitine or glucuronic acid conjugates.

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