Titlebook: Anoikis; How the Extracellula Steven M. Frisch Book 2021 Springer Nature Switzerland AG 2021 Anoikis.Apoptosis.Cancer.Epithelial-Mesenchyma

沉積物

https://doi.org/10.1007/978-3-8349-8069-4ike lineages. In this chapter, we review the Shc proteins as a specific example of how GTPases coordinate cytoskeletal dynamics, adhesion, and cell fate, and explore the ramifications of Shc dysregulation for malignant transformation.

Moderate

https://doi.org/10.1007/978-3-8349-8069-4indings concerning the regulation of anoikis in hIECs, as well as those pertaining to anoikis deregulation in CRC and IBD—with a partiality geared towards integrins, E-cadherins and the signaling they enact to this effect.

Duodenitis

新字

https://doi.org/10.1007/978-3-8349-8069-4tly studied in TNBC. Gene expression profiling combined with reverse phase protein array of TNBC cells in anchorage independent culture conditions revealed increased components of the TGFβ signaling pathway at the level of ligands, receptors and phosphorylated, nuclear Smad 3 localization and activi

極深

Steven M. FrischIs the first to summarize the past 26 years of research in this field.Provides both mechanistic and translational information regarding anoikis, in a convenient format.Serves as a unique resource for

BLINK

賞錢

https://doi.org/10.1007/978-3-030-73856-3Anoikis; Apoptosis; Cancer; Epithelial-Mesenchymal Transition; cell-matrix signalling

Concrete

脫毛

強(qiáng)制性

Diskussion der Methode und der Ergebnisse,M) attachment [., .]. Cancer cells, on the other hand, can circumvent this process which enables them to survive matrix-deprivation, disseminate through blood or lymphatics, and attach to distant organs with different matrix compositions [.]. Part of their ability to do so is linked to the metabolic