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Titlebook: Anoikis; How the Extracellula Steven M. Frisch Book 2021 Springer Nature Switzerland AG 2021 Anoikis.Apoptosis.Cancer.Epithelial-Mesenchyma

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樓主
發(fā)表于 2025-3-21 19:27:54 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Anoikis
期刊簡稱How the Extracellula
影響因子2023Steven M. Frisch
視頻videohttp://file.papertrans.cn/159/158022/158022.mp4
發(fā)行地址Is the first to summarize the past 26 years of research in this field.Provides both mechanistic and translational information regarding anoikis, in a convenient format.Serves as a unique resource for
圖書封面Titlebook: Anoikis; How the Extracellula Steven M. Frisch Book 2021 Springer Nature Switzerland AG 2021 Anoikis.Apoptosis.Cancer.Epithelial-Mesenchyma
影響因子.Anoikis is defined broadly as apoptosis that is inhibited by appropriate cell-matrix interactions.? Normal and tumor cells vary widely in their sensitivity to anoikis, but, in general, metastatic tumor cells are inevitably anoikis-resistant.? In particular, tumor cells that possess acancer stem cellormesenchymalphenotype, arising from the oncogenic Epithelial-Mesenchymal Transition (EMT), are transcriptionally re-programmed to resist anoikis.? While the anoikis response occurs through the mitochondrial pathway typically found in other apoptotic responses (e.g., DNA damage, death receptors, oxidative stress), the regulation of anoikis by cell-matrix signalling is unique and only partially characterized.? The uniqueness of anoikis is: a. regulation by integrins, non-integrin matrix receptors, and the signaling complexes associated with them; b. regulation by metabolic changes occurring in response to attachment/detachment;? c. regulation by oncogenes and tumor suppressor genes d. regulation by tumor microenvironment;? e. regulation by EMT..
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發(fā)表于 2025-3-21 23:26:48 | 只看該作者
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發(fā)表于 2025-3-22 02:35:12 | 只看該作者
https://doi.org/10.1007/978-3-8349-8069-4f neuroectodermal origin and not epithelial in nature. As such, melanoma cells show key differences in specific parts of pathways leading to anoikis resistance. This chapter will focus on the specific mechanisms involved in anoikis resistance in cutaneous melanoma, a poorly studied tumor in this area.
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發(fā)表于 2025-3-22 07:31:10 | 只看該作者
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發(fā)表于 2025-3-22 16:21:27 | 只看該作者
Anoikis Resistance in Melanoma,f neuroectodermal origin and not epithelial in nature. As such, melanoma cells show key differences in specific parts of pathways leading to anoikis resistance. This chapter will focus on the specific mechanisms involved in anoikis resistance in cutaneous melanoma, a poorly studied tumor in this area.
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發(fā)表于 2025-3-22 23:17:43 | 只看該作者
kis, in a convenient format.Serves as a unique resource for .Anoikis is defined broadly as apoptosis that is inhibited by appropriate cell-matrix interactions.? Normal and tumor cells vary widely in their sensitivity to anoikis, but, in general, metastatic tumor cells are inevitably anoikis-resistan
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發(fā)表于 2025-3-23 02:46:47 | 只看該作者
Book 2021ulation by integrins, non-integrin matrix receptors, and the signaling complexes associated with them; b. regulation by metabolic changes occurring in response to attachment/detachment;? c. regulation by oncogenes and tumor suppressor genes d. regulation by tumor microenvironment;? e. regulation by EMT..
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發(fā)表于 2025-3-23 08:08:57 | 只看該作者
d with them; b. regulation by metabolic changes occurring in response to attachment/detachment;? c. regulation by oncogenes and tumor suppressor genes d. regulation by tumor microenvironment;? e. regulation by EMT..978-3-030-73856-3
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