Titlebook: Role of Transcription Factors in Gastrointestinal Malignancies; Ganji Purnachandra Nagaraju,Pallaval Veera‘Bramhac Book 2017 Springer Natu

鉆孔

Talkative

Book 2017mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associat

緊張過(guò)度

YY1 and KLF4: Their Role in Gastrointestinal Malignancies,idence over the years has implicated KLF4 and YY1 in the process of tumorigenesis, significant loopholes still remain. This review is an attempt to evaluate the relative contributions of KLF4 and YY1 to various aspects of GI malignancies.

參考書目

,NF-κB Role and Potential Drug Targets in Gastrointestinal Cancer, in several diseases. NF-κB is actively expressed in many cancers and helps in initiations, cell proliferations, and metastasis of different cancers. The present chapter discusses the role of NF-κB in cancer promotion and different drug targets, targeting NF-κB pathway for the treatment of cancers.

聯(lián)想記憶

Role and Regulation of Transcriptional Factors in Gastric Cancer,leads to gastric cancer. Transcriptional factors’ role in apoptosis, cell cycle, cell proliferation, and metastasis (adhesion, invasion, migration, angiogenesis) is well known and established. The role and regulation of transcriptional factors in relation to gastric cancer was reviewed.

古代

Role of Hypoxia-Inducible Factor (HIF) in the Initiation of Cancer and Its Therapeutic Inhibitors, in the treatment of cancer, and also numerous inhibitors for HIF-1α are available today. This chapter explains the HIF-1α role in cancer and its therapeutic applications that potentially target HIF pathway.

HPA533

Book 2017, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy..

魅力

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Transcription Factors in Gastrointestinal Malignancies,re, targeting these transcriptional factors is an important therapeutic strategy against cancer. In this book, we will discuss some of the important transcriptional factors in depth and further evaluate their role in Gastrointestinal malignancies.

harangue

Activator Protein-1 Transcription Factors in Pathological Cancers,olled by AP-1 transcription factors during cancer advancement. ., we have evaluated the role of transcription factors which provides new insights into mechanisms of regulation of colorectal cancer by AP-1 family transcription factors.