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Titlebook: Role of Transcription Factors in Gastrointestinal Malignancies; Ganji Purnachandra Nagaraju,Pallaval Veera‘Bramhac Book 2017 Springer Natu

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書目名稱Role of Transcription Factors in Gastrointestinal Malignancies
編輯Ganji Purnachandra Nagaraju,Pallaval Veera‘Bramhac
視頻videohttp://file.papertrans.cn/832/831559/831559.mp4
概述This book highlights different transcription factors that are involved in gastro-intestinal cancers.It describes the roles of transcription factors in tumor growth and tumor cell metastasis including
圖書封面Titlebook: Role of Transcription Factors in Gastrointestinal Malignancies;  Ganji Purnachandra Nagaraju,Pallaval Veera‘Bramhac Book 2017 Springer Natu
描述.This book illustrates the importance of transcription factors in gastrointestinal cancer progression and metastasis with regard to understanding the mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associated cancers (esophagus, stomach, colorectal, liver and pancreatic cancers) in connection with specific functional studies like cell cycle, angiogenesis, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy..
出版日期Book 2017
關(guān)鍵詞Gastrointestinal maligancies; Transcription factors; Signaling Pathways; Tumor growth; Drug targets; gene
版次1
doihttps://doi.org/10.1007/978-981-10-6728-0
isbn_softcover978-981-13-3893-9
isbn_ebook978-981-10-6728-0
copyrightSpringer Nature Singapore Pte Ltd 2017
The information of publication is updating

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A. M. V. N. Prathyusha,Renuka Nawadkar,Pallaval Veera Bramhachari
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AP-1: Its Role in Gastrointestinal Malignancies,1 in cancer appear to rely on composition of AP-1 dimers and type, stage, and genetic basis of cancer. c-Jun protein, one of the subunits of AP-1 up on activation, is expressed primarily at invasive front in carcinomas leading to the proliferation of malignant cells. Thus, c-Jun mainly has oncogenic
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