| 書目名稱 | Role of Transcription Factors in Gastrointestinal Malignancies | | 編輯 | Ganji Purnachandra Nagaraju,Pallaval Veera‘Bramhac | | 視頻video | http://file.papertrans.cn/832/831559/831559.mp4 | | 概述 | This book highlights different transcription factors that are involved in gastro-intestinal cancers.It describes the roles of transcription factors in tumor growth and tumor cell metastasis including | | 圖書封面 |  | | 描述 | .This book illustrates the importance of transcription factors in gastrointestinal cancer progression and metastasis with regard to understanding the mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associated cancers (esophagus, stomach, colorectal, liver and pancreatic cancers) in connection with specific functional studies like cell cycle, angiogenesis, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy.. | | 出版日期 | Book 2017 | | 關鍵詞 | Gastrointestinal maligancies; Transcription factors; Signaling Pathways; Tumor growth; Drug targets; gene | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-10-6728-0 | | isbn_softcover | 978-981-13-3893-9 | | isbn_ebook | 978-981-10-6728-0 | | copyright | Springer Nature Singapore Pte Ltd 2017 |
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