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Titlebook: High-Throughput Screening Assays in Toxicology; Hao Zhu,Menghang Xia Book 2022Latest edition This is a U.S. government work and not under

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發(fā)表于 2025-3-21 17:07:49 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)High-Throughput Screening Assays in Toxicology
編輯Hao Zhu,Menghang Xia
視頻videohttp://file.papertrans.cn/427/426807/426807.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
叢書(shū)名稱(chēng)Methods in Molecular Biology
圖書(shū)封面Titlebook: High-Throughput Screening Assays in Toxicology;  Hao Zhu,Menghang Xia Book 2022Latest edition This is a U.S. government work and not under
描述This second edition volume expands on the previous edition by exploring the latest advancements in high throughput screening (HTS) in toxicity studies by using in vitro, ex vivo, and in vivo models. This volume also covers the application of artificial intelligence (AI) and data science to curate, manage, and use HTS data. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.?.Cutting-edge and thorough, .High Throughput Screening Assays in Modern Toxicology, Second Edition. is a valuable resource for scientists pursuing chemical toxicology research. This book will aid scientists and researchers in translating new HTS techniques into standardized chemical toxicology assessment tools that can refine, reduce, and replace animal testing.?.
出版日期Book 2022Latest edition
關(guān)鍵詞In vitro screening; In vivo toxicology; 3D cell systems; Toxicity data analysis; HTS assays
版次2
doihttps://doi.org/10.1007/978-1-0716-2213-1
isbn_softcover978-1-0716-2215-5
isbn_ebook978-1-0716-2213-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThis is a U.S. government work and not under copyright protection in the U.S.; foreign copyright pro
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wie der Lebensarbeitszeiten geht ein zunehmender Bedarf an ?know how“ im Sinne von Handlungsanweisungen und/oder -Strategien zur konkreten Umsetzung und Implementation bestimmter neuer Arbeitszeitmodelle einher. Dieser Bedarf st??t allerdings auf zwei erhebliche Barrieren. So gibt es zum einen seite
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Srilatha Sakamuru,Jinghua Zhao,Matias S. Attene-Ramos,Menghang Xiaits ihre Entwicklung, aber auch ihr Einsatz erfolgt interessenbezogen, sie positionieren Akteure und geben ihnen Handlungsm?glichkeiten und -grenzen vor (vgl. z.B. Laske/Weiskopf 1996, S. 325f.). Entsprechend sind Arbeitszeugnisse, ihre Gestaltung und ihr Einsatz von politischer Bedeutung im Rahmen
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?ftigung und Arbeitslosigkeit) machen die fortschreitende Prekarisierung der Erwerbsarbeit deutlich. Konsequenzen für die Besch?ftigten sind etwa ein erh?htes Armuts- und Arbeitslosigkeitsrisiko und zunehmende Verunsicherung. Die Arbeitszufriedenheitsforschung geht auf diese Entwicklungen bisher kau
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Cell-Based Assays to Identify ERR and ERR/PGC Modulatorsncer prognosis. One of the unique features of this transcription factor is the interplay with its cofactors. For instance, certain modulators require the presence of proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) alongside ERRα. Therefore, identification of ERRα agonists and anta
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Identifying CAR Modulators Utilizing a Reporter Gene Assay two possible methods of activation for CAR, direct ligand binding and a ligand-independent method, which makes this a unique nuclear receptor. Both mechanisms require the translocation of CAR from the cytoplasm into the nucleus. Interestingly, CAR is constitutively active and spontaneously localize
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