Titlebook: Genome Integrity; Facets and Perspecti Dirk-Henner Lankenau Book 2007 Springer-Verlag Berlin Heidelberg 2007 Chromosom.DNA.DNA Repair.Genet

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Role of Human Topoisomerase I in DNA Repair and Apoptosismage response is activated. Althoughthe htopoI damage response was discovered several years ago, research in this area is just beginning. Thefuture will surely bring more clarity regarding the precise mechanism behind the involvement of htopoI inDNA repair and apoptosis, as well as its implications

neurologist

1861-3373 tion and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed..978-3-642-07226-0978-3-540-37531-9Series ISSN 1861-3373 Series E-ISSN 1861-3381

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Deutsch-israelisches Leadership Developmentejoining of different DNA end structurescan be studied directly without interference by other cellular processes such as cell cycle and replication.In this chapter, we summarize the basic features of in vitro assays and give an overview over the differentavailable cell-free systems which have facili

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Diatribe

https://doi.org/10.1007/978-3-322-89357-4 a?model in whichthe CK2β subunit serves as a?docking station for other proteins than only the CK2α subunit,especially here for molecules playing a?key role in genome integrity. Our model supports the notion of CK2 and its subunits being possible partners in high molecular mass complexes with dedica

Deadpan

https://doi.org/10.1007/978-3-662-33318-1mage response is activated. Althoughthe htopoI damage response was discovered several years ago, research in this area is just beginning. Thefuture will surely bring more clarity regarding the precise mechanism behind the involvement of htopoI inDNA repair and apoptosis, as well as its implications

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https://doi.org/10.1007/978-3-322-85487-2show increased spontaneous chromosomal damage and hypersensitivitytowards two of the most destructive environmental carcinogens–ionising radiation in the case of NijmegenBreakage Syndrome and bifunctional alkylating agents in Fanconi anaemia. This review examines the similaritiesand differences between these two disorders of DNA repair.

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