Titlebook: Genome Integrity; Facets and Perspecti Dirk-Henner Lankenau Book 2007 Springer-Verlag Berlin Heidelberg 2007 Chromosom.DNA.DNA Repair.Genet

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https://doi.org/10.1007/978-3-322-85487-2e instability syndromes have a?greatly increased cancerrisk as a?major symptom. The complexity of the involvement of the underlying genes in the cellularresponse to DNA damage is well illustrated by the disorders Nijmegen Breakage Syndrome (NBS) and Fanconianaemia (FA). These two Mendelian diseases

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,W?rter zur Einübung der Konsonanten,r responses and transcriptional activation of DNA repair genesfollowing exposure of mammalian cells to genotoxic stress. Functional consequences of induction of DNArepair genes are also briefly discussed.

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Induction of DNA Repair Genes in Mammalian Cells in Response to Genotoxic Stressr responses and transcriptional activation of DNA repair genesfollowing exposure of mammalian cells to genotoxic stress. Functional consequences of induction of DNArepair genes are also briefly discussed.

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Germline Double-Strand Break Repair and Gene Targeting in ,: A?Trajectory System throughout Evolutioxemplified here, recombination tract data reflectthe relatedness of the DSB repair mechanics of SDSA, Break Induced Replication (BIR), Single Strand Annealing(SSA), and the involvement of Holliday junctions (HJs) and non-DSB repair pathways.

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