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Titlebook: Gene Therapy of Cancer; Methods and Protocol Wolfgang Walther Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), unde

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發(fā)表于 2025-3-25 06:30:32 | 只看該作者
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發(fā)表于 2025-3-25 17:48:21 | 只看該作者
f receptor properties for adoptive T-cell therapies. Multiple streams of technological platforms have been developed in the recent decades to genetically modify primary T cells including nonviral platforms such as transposon-based systems (PiggyBac, Sleeping Beauty), TALENs, or CRISPR-Cas9). The pro
25#
發(fā)表于 2025-3-25 22:38:36 | 只看該作者
https://doi.org/10.1007/978-94-017-1053-4two paths of generating antigen-specific T cells, first, T cell stimulation with autologous dendritic cells pulsed with antigen peptide, second, in vivo T cell stimulation with peptide or DNA by gene gun application in a suitable mouse model followed by in vitro enrichment of peptide-reactive T cell
26#
發(fā)表于 2025-3-26 02:28:59 | 只看該作者
https://doi.org/10.1007/978-3-030-50468-7NA vaccines, particularly in large animals and humans, different strategies have been pursued. These vaccination strategies are based on different application routes, schedules and coexpression of immunomodulatory molecules as adjuvants. Our mouse tumor model offers the possibility to investigate He
27#
發(fā)表于 2025-3-26 05:37:23 | 只看該作者
Greenhouse Gases: A Historical Perspective,ill themselves by expressing toxic ribosome-inactivating proteins. Plasmids are stable and easy-to-produce vectors, but they have some disadvantages due to the bacterial backbone. Applying the minicircle technology, this problem can be solved with manageable effort in a well-equipped laboratory. Wit
28#
發(fā)表于 2025-3-26 09:54:45 | 只看該作者
https://doi.org/10.1007/978-94-017-7462-8rse modes of action, the . enterotoxin (CPE) is in focus to treat solid cancers. This toxin targets the tight junction proteins claudin-3 and -4 (Cldn-3/4), which are frequently overexpressed in solid cancers. Binding to these claudins induces pore formation in the host cell plasma membrane leading
29#
發(fā)表于 2025-3-26 16:43:01 | 只看該作者
Climate Change and AgrometeorologyNAs), and guide RNAs (gRNAs), represent a novel class of modalities that not only increase the molecular diversity of medications but also expand the range of druggable targets. To develop noncoding RNA therapeutics for the treatment of cancer diseases, we have established a novel robust RNA bioengi
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發(fā)表于 2025-3-26 18:59:37 | 只看該作者
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