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Titlebook: Gene Therapy of Cancer; Methods and Protocol Wolfgang Walther Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), unde

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發(fā)表于 2025-3-21 17:45:44 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Gene Therapy of Cancer
副標(biāo)題Methods and Protocol
編輯Wolfgang Walther
視頻videohttp://file.papertrans.cn/382/381986/381986.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: Gene Therapy of Cancer; Methods and Protocol Wolfgang Walther Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), unde
描述.This third edition provides new and updated chapters on gene therapeutic strategies of cancer. Chapters guide readers through suicide and oncolytic gene therapy, gene replacement and gene suppression therapy, vector development and refinement, immunogene therapy, TCR and CAR engineering, tumor vaccination using DNA or RNA vaccines, and antitumoral immune stimulation at different levels. Written in the format of the highly successful?.Methods in Molecular Biology?.series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols...?..Authoritative and cutting-edge,?.Gene Therapy of Cancer: Methods and Protocols, Third Edition .aims to be a?useful and practical guide to new researchers and experts looking to expand their knowledge. .
出版日期Book 2022Latest edition
關(guān)鍵詞CAR-T cells; Suicide gene therapy; Gene replacement; Gene suppression; Oncolytic therapy
版次3
doihttps://doi.org/10.1007/978-1-0716-2441-8
isbn_softcover978-1-0716-2443-2
isbn_ebook978-1-0716-2441-8Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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TCR Gene Therapy for Cancertwo paths of generating antigen-specific T cells, first, T cell stimulation with autologous dendritic cells pulsed with antigen peptide, second, in vivo T cell stimulation with peptide or DNA by gene gun application in a suitable mouse model followed by in vitro enrichment of peptide-reactive T cell
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Gene Gun Her2/neu DNA Vaccination: Evaluation of Vaccine Efficacy in a Syngeneic Her2/neu Mouse TumoNA vaccines, particularly in large animals and humans, different strategies have been pursued. These vaccination strategies are based on different application routes, schedules and coexpression of immunomodulatory molecules as adjuvants. Our mouse tumor model offers the possibility to investigate He
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Construction of Minicircle Suicide Genes Coding for Ribosome-Inactivating Proteinsill themselves by expressing toxic ribosome-inactivating proteins. Plasmids are stable and easy-to-produce vectors, but they have some disadvantages due to the bacterial backbone. Applying the minicircle technology, this problem can be solved with manageable effort in a well-equipped laboratory. Wit
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