Titlebook: Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury; Proceedings of the 1 Kenneth V. Honn,Lawrence J. Marnett,Thomas L. W

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Prevention of Peroxide Produced DNA Strand Scission in Human Tumor Cells by Lipoxygenase Inhibitorsor peroxides cannot be exclusively attributed to chemical interactions. That is, the “indirect” action of radiation may be mediated through rapidly initiated cellular mechanisms which lead to DNA scission rather than by hydroxyl radical reactions on the DNA molecule itself. The following experiments

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Conference proceedings 1991participation of lipid oxidation in conversion of procarcinogens, positive and negative modulation of tumor growth, immunomodulation, tissue injury, and yet protection and enhancement of cancer therapy, necessitated scientific interaction to sort out and understand these complex and sometimes contra

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Liming Deng,Qiujin Chen,Yanyan Zhanglls which do not participate in the oxidative conversion of arachidonic acid into reactive intermediates. Table 1 indicates that the red blood cell and the lymphocyte (3) cannot metabolize arachidonic acid by either the cyclooxygenase or lipoxygenase pathways. Normally, one considers most cells in t

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Eicosanoids and Other Bioactive Lipids in Cancer and Radiation InjuryProceedings of the 1

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Kenneth V. Honn,Lawrence J. Marnett,Thomas L. Wald

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