Titlebook: Drug-Induced Liver Toxicity; Minjun Chen,Yvonne Will Book 2018 Springer Science+Business Media, LLC, part of Springer Nature 2018 Acute li

下邊深陷

Drug-Induced Liver Toxicity978-1-4939-7677-5Series ISSN 1557-2153 Series E-ISSN 1940-6053

CONE

Minjun Chen,Yvonne WillIncludes cutting-edge techniques for the study of DILI.Contains key implementation advice from the experts.Features detail essential for labs, from basic research through to clinical action

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受辱

Sensors,me cases parent drug, elicit a variety of biochemical consequences such as covalent binding and oxidative stress which trigger signal transduction, transcription factors, mitochondrial and endoplasmic reticulum (ER) stress which can lead directly to cell death or activate adaptive responses which mi

CLAP

Background Agents and Local Notifications, major hurdle and is recognized to be a major cause of drug attrition and market withdrawal. DILI impacts many different sectors of society including patients, public health systems, health insurers and the pharmaceutical industry. Animal models are very efficient at detecting direct, dose-dependent

激怒

endarterectomy

爭(zhēng)論

Brain Injury and Work Performanceation groups, and difficulty in annotation of drugs, especially for the drugs that have been on the market for a short period of time. DILI remains a challenge for the industry and regulatory agencies. Assessing DILI risk in humans is important to assist drug development for the industry and to info

梯田

Harbor