Titlebook: DNA and RNA Profiling in Human Blood; Methods and Protocol Peter Bugert Book 2009 Humana Press 2009 Blood cell antigens.Disease markers.Gen

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書目名稱DNA and RNA Profiling in Human Blood影響因子(影響力)




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Single Base Extension in Multiplex Blood Group Genotypingrnative strategy to phenotyping blood is to assay genomic DNA for the associated single nucleotide polymorphisms (SNPs). A multiplex PCR coupled with a single base oligonucleotide extension assay using genomic DNA can identify SNPs related to D, C/c, E/e, S/s, K/k, Kp., Fy., Fy0 (–33 promoter silenc

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Pyrosequencing of Toll-Like Receptor Polymorphisms of Functional Relevances, cancer, or infections and genetically determined susceptibility to danger signals may influence the development of inflammatory diseases. Members of the ‘toll-like receptor’ (TLR) family are pivotal molecules in the activation of the innate immune system and specifically recognize structurally co

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High-Throughput Multiplex HLA-Typing by Ligase Detection Reaction (LDR) and Universal Array (UA) Appriation involves differences in single DNA nucleotides, and is thus termed single nucleotide polymorphism (SNP). The need for improvement in throughput and reliability of traditional techniques makes it necessary to develop new technologies. Thus the past few years have witnessed an extraordinary su

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Medium- to High-Throughput SNP Genotyping Using VeraCode Microbeadsn genetic variation and disease. Discoveries made by such whole-genome association studies often spur further interest in surveying more focused subsets of SNPs for validation or research purposes. Here we describe a new SNP genotyping platform that is flexible in assay content and multiplexing (up

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