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Titlebook: Amine Oxidases and Their Impact on Neurobiology; Proceedings of the 4 Peter Riederer,Moussa B. H. Youdim Conference proceedings 1990 Spring

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21#
發(fā)表于 2025-3-25 04:25:54 | 只看該作者
The interaction of transport mechanisms and intracellular enzymes in metabolizing systemsivity of these intracellular enzymes, it is unlikely that either COMT or MAO is ever saturated in vivo. However, in vitro saturation of extraneuronal COMT and MAO reveals that extraneuronal COMT is a high-affinity, but extraneuronal MAO a low-affinity enzyme. Hence, membrane-bound COMT appears to be
22#
發(fā)表于 2025-3-25 08:41:34 | 只看該作者
The mechanism of action of antidepressants revisedmore selective antidepressants led to new reflections upon the mechanism of action. On the level of transmitters, α.upregulation, increased activity of the dopaminergic system, an alteration in the balance between the different transmitter systems, are reported and seem to be important. Most promisi
23#
發(fā)表于 2025-3-25 13:14:54 | 只看該作者
24#
發(fā)表于 2025-3-25 15:48:40 | 只看該作者
,Die rechtliche Identit?t Gesamttirols,ivity of these intracellular enzymes, it is unlikely that either COMT or MAO is ever saturated in vivo. However, in vitro saturation of extraneuronal COMT and MAO reveals that extraneuronal COMT is a high-affinity, but extraneuronal MAO a low-affinity enzyme. Hence, membrane-bound COMT appears to be
25#
發(fā)表于 2025-3-25 23:44:04 | 只看該作者
26#
發(fā)表于 2025-3-26 01:56:04 | 只看該作者
https://doi.org/10.1007/978-3-658-34957-8/day, both analogues produced greater inhibition of MAO-A and -B than did tranylcypromine. 4-Methoxytranylcypromine and 4-fluorotranylcypromine were similar in their extent of inhibition of MAO-B but the former was more potent than the latter at inhibition MAO-A.
27#
發(fā)表于 2025-3-26 06:55:22 | 只看該作者
28#
發(fā)表于 2025-3-26 09:20:01 | 只看該作者
29#
發(fā)表于 2025-3-26 15:35:39 | 只看該作者
30#
發(fā)表于 2025-3-26 18:25:49 | 只看該作者
The expression of human MAO-A and B genes and adult brains. The tissue distribution of these transcripts was determined. Small intestine and placenta express, in addition to the MAO-A 5Kb transcript, a 2Kb transcript determined to lack a 3′ flanking region. MAO-A appeared prior to MAO-B in the fetal brain, whereas both MAO-A and B were fou
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