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Titlebook: Amine Oxidases and Their Impact on Neurobiology; Proceedings of the 4 Peter Riederer,Moussa B. H. Youdim Conference proceedings 1990 Spring

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11#
發(fā)表于 2025-3-23 13:24:14 | 只看該作者
12#
發(fā)表于 2025-3-23 15:49:59 | 只看該作者
Stylbasole analogues of MPTP as monoamine oxidase (MAO) substrates B type of MAO was found. Influence of substrate structure on its biotransformation effectiveness is realized by the principle — “better binding-worse catalysis”. MAO inactivation during the reaction is appeared to be realized as result of product inhibition and perhaps of substrate inhibition.
13#
發(fā)表于 2025-3-23 18:12:56 | 只看該作者
https://doi.org/10.1007/978-3-662-67441-3.g. white matter. When the brains from the controls were compared with those with AD, the mean values for .H-deprenyl binding was higher in the latter group, however, more generalised than previously reported.
14#
發(fā)表于 2025-3-23 23:02:17 | 只看該作者
https://doi.org/10.1007/978-3-531-94092-2unds can be used as VPA prodrugs. Both compounds, however, at relatively low doses exhibited distinct tremor effects in mice and rats. They also potentiate the convulsant effect induced by mercaptopropionic acid (MPA).
15#
發(fā)表于 2025-3-24 05:26:13 | 只看該作者
https://doi.org/10.1007/978-3-476-03712-1 analogues in which this position is blocked with a substituent. In preliminary acute studies at a dose of 0.1 mmol/kg .-chloro-PLZ was found to have a similar effect to PLZ on the inhibition of MAO and to lead to an elevation of catecholamines and 5-hydroxytryptamine (5-HT) in rat whole brain.
16#
發(fā)表于 2025-3-24 07:13:47 | 只看該作者
Handels-, Wechsel- und Scheckrecht,support the hypothesis of a glycine-mediated anticonvulsant activity for milacemide and suggest that the increased formation of UK. to the detriment of glycinamide might account for the lack of protection against bicuculline-induced lethality by milacemide in rats.
17#
發(fā)表于 2025-3-24 13:25:56 | 只看該作者
18#
發(fā)表于 2025-3-24 15:12:46 | 只看該作者
MAO activity, metabolism and anticonvulsant activity of milacemide in rats and micesupport the hypothesis of a glycine-mediated anticonvulsant activity for milacemide and suggest that the increased formation of UK. to the detriment of glycinamide might account for the lack of protection against bicuculline-induced lethality by milacemide in rats.
19#
發(fā)表于 2025-3-24 22:28:26 | 只看該作者
20#
發(fā)表于 2025-3-25 01:55:26 | 只看該作者
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