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Mechanisms of Resistance to Camptothecinsarent compound is a naturally occurring alkaloid found in the Chinese plant .. This compound was first identified in the 1960s in a screen of plant extracts for antineoplastic drugs (.). Subsequently, many derivatives of the parent compound have been synthesized, including topotecan, irinotecan, 9-a

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,Multiobjective Optimization of Long Irregular RC Bridges’ Piers Subjected to Strong Motions and Deflinear dynamic behavior. This stems from the possible influence of higher modes in the overall seismic behavior, among other factors (Kappos et al., in Seismic design and assessment of bridges, inelastic methods of analysis and case studies, Springer, New York, 2012), making the analysis in many cas

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