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Titlebook: Stress Response; Methods and Protocol John M. Walker,Stephen M. Keyse Book 2000 Humana Press 2000

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發(fā)表于 2025-3-21 17:11:56 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Stress Response
副標(biāo)題Methods and Protocol
編輯John M. Walker,Stephen M. Keyse
視頻videohttp://file.papertrans.cn/880/879592/879592.mp4
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: Stress Response; Methods and Protocol John M. Walker,Stephen M. Keyse Book 2000 Humana Press 2000
描述Mammalian cells have evolved a complex multicomponent machinery that enables them to sense and respond to a wide variety of potentially toxic agents present in their environment. These stress responses are often associated with an increased cellular capacity to tolerate normally lethal levels of an insult. The realization that the mammalian stress response may be intimately linked with many human diseases, including rheumatoid arthritis, ischemia, fever, infection, and cancer, has led to an explosion of interest in this research area. Stress Response: Methods and Protocols brings together a diverse array of practical methodologies that may be employed to address various aspects of the response of mammalian cells to environmental stress. The p- tocols are carefully described by authors who have both devised and succe- fully employed them, and they represent a mixture not only of well-established techniques, but also new technologies at the leading edge of research. The areas covered include the detection and assay of stress-induced damage, the acti- tion of signal transduction pathways, stress-inducible gene expression, and stress protein function. Although no volume of this size ca
出版日期Book 2000
版次1
doihttps://doi.org/10.1385/1592590543
isbn_softcover978-1-61737-097-7
isbn_ebook978-1-59259-054-4Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2000
The information of publication is updating

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Analysis of the Role of the AMP-Activated Protein Kinase in the Response to Cellular Stress stress that affects the ability of the cell to maintain a high ATP: ADP ratio (normally approx 10:1 in an unstressed cell) leads to activation of the AMPK cascade. Cellular stresses can do this either by inhibiting ATP production or by increasing ATP consumption, and stresses shown to cause AMPK ac
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發(fā)表于 2025-3-22 03:16:35 | 只看該作者
Detection and Activation of Stress-Responsive Tyrosine Kinaseshydrogen peroxide or ultraviolet (UV) radiation has been found to activate tyrosine kinases associated with the antigen receptor in T- and B-cells, giving rise to signaling patterns similar to those induced by direct antigen-receptor stimulation (.–.).
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Detection and Purification of a Multiprotein Kinase Complex from Mammalian Cellsay already exist as part of a multiprotein complex that functions to maintain their steady-state activity and, at the same time, properly position the enzymes so as to respond to incoming signals from the cellular environment. Such complexes could be regulated through control of their subcellular lo
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Book 2000blished techniques, but also new technologies at the leading edge of research. The areas covered include the detection and assay of stress-induced damage, the acti- tion of signal transduction pathways, stress-inducible gene expression, and stress protein function. Although no volume of this size ca
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Rodney L. Levine,Nancy Wehr,Joy A. Williams,Earl R. Stadtman,Emily Shacter
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發(fā)表于 2025-3-23 04:26:39 | 只看該作者
These methods, however, are still in the developmental stages and are not available in foolproof form for use by design engineers..There should be no doubt that, at present and for the foreseeable future, the computer and wind tunnel are and will be dependent upon each other for the practical solution of complex separated flow problems.
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