| 書(shū)目名稱(chēng) | Stress Response | | 副標(biāo)題 | Methods and Protocol | | 編輯 | John M. Walker,Stephen M. Keyse | | 視頻video | http://file.papertrans.cn/880/879592/879592.mp4 | | 叢書(shū)名稱(chēng) | Methods in Molecular Biology | | 圖書(shū)封面 |  | | 描述 | Mammalian cells have evolved a complex multicomponent machinery that enables them to sense and respond to a wide variety of potentially toxic agents present in their environment. These stress responses are often associated with an increased cellular capacity to tolerate normally lethal levels of an insult. The realization that the mammalian stress response may be intimately linked with many human diseases, including rheumatoid arthritis, ischemia, fever, infection, and cancer, has led to an explosion of interest in this research area. Stress Response: Methods and Protocols brings together a diverse array of practical methodologies that may be employed to address various aspects of the response of mammalian cells to environmental stress. The p- tocols are carefully described by authors who have both devised and succe- fully employed them, and they represent a mixture not only of well-established techniques, but also new technologies at the leading edge of research. The areas covered include the detection and assay of stress-induced damage, the acti- tion of signal transduction pathways, stress-inducible gene expression, and stress protein function. Although no volume of this size ca | | 出版日期 | Book 2000 | | 版次 | 1 | | doi | https://doi.org/10.1385/1592590543 | | isbn_softcover | 978-1-61737-097-7 | | isbn_ebook | 978-1-59259-054-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2000 |
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