Titlebook: Shock, Sepsis, and Organ Failure; First Wiggers Bernar Günther Schlag,Heinz Redl,John H. Siegel Conference proceedings 1990 Springer-Verlag

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Carl J. Wiggers, M.D.e of the most eminent giants in the area of shock research and cardiovascular physiology. He was born on May 28, 1883 in Davenport, Iowa. At that time, this was a city of near 50,000 population on the Mississippi River and had traditionally been a starting point for immigration to the western aspect

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Claude Bernardarious schools which he attended were run by the Jesuit order and consequently he received a very thorough and exact education. On completion of his early education Bernard apprenticed himself to a pharmacist. However, at the same time he developed a very strong interest in theatre. He wrote a Vaude

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Quantification of Organ Failureultiple organ failure (MOF) has been described by Baue (Baue 1975) as a sequence of organ failures initiated by shock, trauma or sepsis. The definition of MOF is handled arbitrarily, the number and rank of the organ systems involved varies and depends on the individual judgement of the investigators

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Endothelium as the Interface between Blood and Organ in the Evolution of Organ Failureg blood with its cellular components. To perform their task, the EC are able to form a barrier against molecular and cellular components and thus provide a highly specific permeability (Machovich, 1988).

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Carl J. Wiggers, M.D. prominent rathskeller in the city. During this time period these establishments served as places of social gathering, especially for the numerous german speaking people who lived in this very fertile agricultural area.

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