Titlebook: Regulation of Immune Gene Expression; Marc Feldmann,Andrew McMichael Book 1986 The Humana Press Inc. 1986 Antigen.DNA.chromosome.evolution

親屬

Book 1986rs. M. Crumpton, M. Feldmann, A. McMichael, and E. Simpson, and advised by many friends and colleagues. The immune response gene workshops that took place were based on the need to understand why certain experimental animal strains were high responders and others were low responders. It was assumed

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Structure/Function Relationships Among Murine Class II Molecules: Sequence Analysis of I-A cDNA Clon(1, 2). Recent studies using either anti-Ia antisera or monoclonal antibodies to block immune responses strongly suggest that la antigens are the products of Ir genes (3–5), but how a limited number of Ia antigens differentially regulate responses to a myriad of antigens is yet to be resolved. Presu

關(guān)節(jié)炎

Organisation and Evolution of Mouse Major Histocompatibility Genesharacterised. Since then, an extraordinary amount of information concerning the structure, organisation and expression of class I genes has been gathered. It is my intention in this report to present an overview of these structural data and show how they have shaped our current understanding of the

皮薩

penance

Molecular Genetics of Human Ia Antigenschromosome 6. Like in other animal systems, these proteins are highly polymorphic in the human population and they are responsible for the phenomenon of Ia restriction in antigen presentation and T cell recognition. Three kinds of class II antigens have been identified in man, HLA-DR, -DQ, (formerly

Climate

Polymorphism in the HLA-D Regiondifferent loci have widely different degrees of polymorphism. Examination of the sequences for features associated with the polymorphic exons reveals clustering of CG dinucleotides, along with a high level of G & C nucleotides. However, these features are not particularly associated with the polymor

偽造

Biochemical Diversity of the Human MHC Class II Antigensp procedure of biochemical modifications, each contributing to the final complexity of the system. A precise knowledge of the structural diversity of the human Ia antigens at the protein level is thus required in order to better understand the mechanisms underlying the function of MHC class II antig

lipids

The T-Cell Receptor/T3 Complex T-lymphocytes (T-cells) mediate the antigen specific cellular immune response. Antigen is recognized by receptors on the surface of T-cells; this recognition does not involve native antigen in a soluble form. Rather, the recognition of antigen by T cell surface receptors depends on the expression o

Misgiving

TERRA

Activation of Precursor and Mature T Lymphocytes via the 50KD T11 Moleculeentification of the human T cell antigen receptor as a surface complex comprised of a clonotypic 90KD Ti heterodimer and three monomorphic 20/25KD T3 molecules (gamma, delta and epsilon) (1–5). Upon binding to the surface of a clone, monoclonal antibodies to either the T3 component or its associated