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Titlebook: Regulation of Immune Gene Expression; Marc Feldmann,Andrew McMichael Book 1986 The Humana Press Inc. 1986 Antigen.DNA.chromosome.evolution

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發(fā)表于 2025-3-21 19:58:30 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Regulation of Immune Gene Expression
編輯Marc Feldmann,Andrew McMichael
視頻videohttp://file.papertrans.cn/826/825683/825683.mp4
叢書名稱Experimental Biology and Medicine
圖書封面Titlebook: Regulation of Immune Gene Expression;  Marc Feldmann,Andrew McMichael Book 1986 The Humana Press Inc. 1986 Antigen.DNA.chromosome.evolution
描述This book encompasses the proceedings of a conference held at Trinity College, Oxford on September 21-25, 1985 organized by a committee comprised of Drs. M. Crumpton, M. Feldmann, A. McMichael, and E. Simpson, and advised by many friends and colleagues. The immune response gene workshops that took place were based on the need to understand why certain experimental animal strains were high responders and others were low responders. It was assumed that identification of the immune response (Ir) genes and definition of their products would explain high and low responder status. Research in the ensuing years has identified the Ir gene products involved in antibody responses as the la antigens, or MHC Class II antigens. These proteins are now well defined as members of the immunoglobulin gene superfamily, and their domain structure is known. Epitopes have been defined by multiple mono- clonal antibodies and regions of hypervariability identified. Their genes have been identified and cloned. The basic observation of high and low responsive- ness to antigen is still not understood in mechanistic terms, however, at either the cellular or molecular level. This is because the rate of progres
出版日期Book 1986
關(guān)鍵詞Antigen; DNA; chromosome; evolution; gene expression; genes; genetics; molecular biology; recombination; tran
版次1
doihttps://doi.org/10.1007/978-1-4612-5014-2
isbn_softcover978-1-4612-9399-6
isbn_ebook978-1-4612-5014-2
copyrightThe Humana Press Inc. 1986
The information of publication is updating

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