Titlebook: Recent Progress in Failing Heart Syndrome; Shigetake Sasayama (Professor of Medicine),Hiroyuk Book 1991 Springer-Verlag Tokyo 1991 adaptat

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Optimal Left Ventricle Versus Optimal Afterload, long as the heart was capable of responding to the command of the regulatory system. Once the heart failed to respond normally to the regulatory system, however, the optimality of ventricular-arterial coupling as defined above was no longer maintained.

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Therapeutic Effects of the Left Ventricular Assist System on Myocardial Ischemia,e levels, which influenced cardiac energy metabolism, were evaluated under LVAS pumping. High energy phosphate levels showed no change in the normal myocardium by LVAS pumping. LVAS pumping reserved high energy phosphate concentrations in the ischemic myocardium and prevented the rise of catecholami

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