Titlebook: Quantification of Circulating Proteins; Theory and applicati Wim Th. Hermens,George M. Willems,Marja P. Visser Book 1982 Martinus Nijhoff P

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Assessment of Myocardial Damage from Plasma Levels of Cardiac Enzymes maximal levels of aspartate aminotransferase (AST) or latate dehydrogenase (LDH) and histologically assessed infarct size after experimental infarction in dogs [334,399,82]. Although significant correlations were found, these were insufficiently high to allow accurate estimation of infarct size fro

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Changes in Circulating Mass of Plasma Proteins during the Acute Phase Responseal infarction. This so-called acute phase response consists of a prolonged increase of plasma concentrations for fibrinogen, alpha.-antitrypsin, haptoglobin and alpha.-acid glycoprotein. Moreover, there appears in the plasma a considerable quantity of a protein, called C-reactive protein, which norm

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Dose-Calculation of Blood Coagulation Factors for Infusion Therapyrecursors of active coagulation factors. The process of coagulation may be initiated by various triggers and consists of sequential activation of coagulation factors resulting in activation of fibrinogen and formation of a fibrin clot. Most blood coagulation factors have been discovered due to the e

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Book 1982 of protein molecules. The first quanti- tative studies on the turnover and distribution of plasma pro- teins were made around 1950, after the introduction of radio- labeled protein preparations. Around 1970, another development in quantitative interpre- tation of circulating proteins was initiated

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Introductionwer than in tissues and their presence in plasma is considered as the result of normal leakage of proteins from cells or as a sign of cell death. The large majority of circulating tissue proteins consists of enzymes that catalyse specific intracellular reactions. Therefore they may also be referred to as circulating tissue enzymes.

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Sources of Error in Quantification of Circulating Proteinsis of disappearance curves. High values for transcapillary escape rates of proteins, as reported in some early studies with radiolabeled proteins, did not cause any doubts about experimental validity.

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