| 書目名稱 | Nuclear Pore Complexes in Genome Organization, Function and Maintenance | | 編輯 | Maximiliano D’Angelo | | 視頻video | http://file.papertrans.cn/669/668647/668647.mp4 | | 概述 | Clear description of the current knowledge in genome organization.Exposes new concepts of the roles of nuclear pore complexes in genomic organization and genome protection/maintenance.A unique source | | 圖書封面 |  | | 描述 | The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosi | | 出版日期 | Book 2018 | | 關(guān)鍵詞 | Genome Organisation; Genomic Stability; Nuclear Pore Complexes; Nuclear Transport; Nucleus; gene expressi | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-71614-5 | | isbn_softcover | 978-3-319-89088-3 | | isbn_ebook | 978-3-319-71614-5 | | copyright | Springer International Publishing AG 2018 |
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書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance影響因子(影響力)
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance影響因子(影響力)學(xué)科排名
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance網(wǎng)絡(luò)公開度
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance被引頻次
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance被引頻次學(xué)科排名
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance年度引用
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance年度引用學(xué)科排名
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance讀者反饋
書目名稱Nuclear Pore Complexes in Genome Organization, Function and Maintenance讀者反饋學(xué)科排名
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