| 書目名稱 | Mucosal Delivery of Biopharmaceuticals | | 副標(biāo)題 | Biology, Challenges | | 編輯 | José das Neves,Bruno Sarmento | | 視頻video | http://file.papertrans.cn/640/639833/639833.mp4 | | 概述 | Explores the biology of mucosal tissues and their interactions with biopharmaceuticals and their delivery systems.Highlights the biological features justifying the use of different human mucosa as del | | 圖書封面 |  | | 描述 | Biopharmaceutical medicines, the newest class of therapeutics, are quite heterogeneous and include a range of molecules such as proteins, peptides, vaccines and nucleic acids, with use in virtually all therapeutic fields (e.g. cancer and infectious diseases, vaccination, metabolic dysfunctions) and diagnostics. This edited book gives a concise and up-to-date overview of the biological features justifying the use of different human mucosa as delivery routes for biopharmaceuticals, the technological strategies that have been followed so far regarding the optimization of mucosal potentialities as well as the challenges that arise with the advent of new biopharmaceutical drugs and alternative means of administration. Following a brief introduction, the first section addresses general aspects of the biology of mucosal tissues and their unique aspects toward beneficial or deleterious interaction with biopharmaceuticals and their delivery systems. The second part reviews the different delivery strategies that have recently been investigated for different mucosal sites. The third section describes the development and clinical applications of drug delivery systems and products enclosing bio | | 出版日期 | Book 2014 | | 關(guān)鍵詞 | biopharmaceuticals; drug delivery; mucoadhesion; mucosal barrier; permeation | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4614-9524-6 | | isbn_softcover | 978-1-4899-7838-7 | | isbn_ebook | 978-1-4614-9524-6 | | copyright | Springer Science+Business Media New York 2014 |
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