Titlebook: Mechanisms of Anesthetic Action in Skeletal, Cardiac, and Smooth Muscle; Thomas J. J. Blanck,David M. Wheeler Book 1991 The Editor(s) (if

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Mechanisms of Anesthetic Action in Skeletal, Cardiac, and Smooth Muscle978-1-4684-5979-1Series ISSN 0065-2598 Series E-ISSN 2214-8019

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Halothane Inhibits Binding of Calcium Channel Blockers to Cardiac Sarcolemmaic changes in intracellular calcium which occur during contraction. These sites are the sarcolemma, the sarcoplasmic reticulum, and the myofibrils. This paper is directed towards our investigations of one constituent of the sarcolemma, the voltage-dependent calcium channel (VDCC), and its probable alteration by the volatile anesthetic, halothane.

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Contribution of the Known Subcellular Effects of Anesthetics to Their Negative Inotropic Effect in Iscles and left atrial muscles to evaluate the relative contribution of anesthetic effects on the transsarcolemmal Ca. influx, on the function of the sarcoplasmic reticulum, and on the response of the myofibril.

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斥責(zé)

Interactions of Fatty Acids with the Calcium Release Channel in Malignant HyperthermiaCa. regulation and on caffeine, halothane and succinylcholine action in normal and MH muscle. Additionally, since phenytoin has been suggested to antagonize MH,. its effects on Ca. regulation and fatty acid metabolism have been examined.

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Effects of Volatile Anesthetics on Cardiac Sarcoplasmic Reticulum as Determined in Intact Cellst the differences in negative inotropic potency among these agents are a consequence of their actions at the SR, we sought to document differences in effect at the SR for all three commonly used agents.

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反對(duì)

The Effects of Volatile Anesthetics on the Calcium Sensitivity of Cardiac Myofilamentsrrently used anesthetics, halothane, enflurane, and isoflurane.. This chapter will review the physiological properties of the contractile proteins and the experimental studies on volatile anesthetic effects.