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Titlebook: Manual of Biological Markers of Disease; W. J. Venrooij,R. N. Maini Book 1996 Springer Science+Business Media Dordrecht 1996 Antigen.Labor

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書目名稱Manual of Biological Markers of Disease
編輯W. J. Venrooij,R. N. Maini
視頻videohttp://file.papertrans.cn/624/623488/623488.mp4
圖書封面Titlebook: Manual of Biological Markers of Disease;  W. J. Venrooij,R. N. Maini Book 1996 Springer Science+Business Media Dordrecht 1996 Antigen.Labor
描述.Section A: Methods of Autoantibody Detection. .This Section provides well structured protocols for autoantibodydetection. Step-by-step procedures are accompanied by explanatorynotes and comments, clear diagrams, line illustrations and excellentphoto illustrations. Extensive literature references lead the way tofurther background information. The methods presented were validatedby more than 40 leading laboratories active in sera analysis, whichindicates that these methods have been found to be practically usefuland lead to consistent inter-laboratory results: consensus inautoantibody detection. ..Section B: Autoantigens. .This Section contains the first compilation of full, detailedinformation on autoantigens related to important autoimmune diseases.The chapters are all structured according to an easy-reference fixedtemplate structure: specific detection methods, cellular localization,biochemical characteristics, function, cDNA and derived amino acidsequence, gene structure, B- and T-cell epitopes and lists ofpublished monoclonal antibodies. The text is greatly enhanced by manybeautiful schematic figures and photo illustrations. As in Section A,extensive literature references are p
出版日期Book 1996
關(guān)鍵詞Antigen; Laboratory; autoimmune disease; autoimmunity; diseases; internal medicine
版次1
doihttps://doi.org/10.1007/978-94-011-5444-4
isbn_softcover978-0-7923-4243-4
isbn_ebook978-94-011-5444-4
copyrightSpringer Science+Business Media Dordrecht 1996
The information of publication is updating

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Methods to detect autoantibodies to neutrophilic granulocytes]. The morphology and content of a granulocyte is given in Fig. 1. Autoantibodies to surface components of neutrophils are considered to be extremely rare, and neutropenias found in relation to autoimmune diseases are most likely induced by circulating immune complexes interacting with and thereby activating neutrophils [5, 6, 7].
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Standards and reference preparationsto standardize the method. This, however, has never appeared to be practical, since most laboratory workers are individualists [10]. But even if they would like to submit their work to rules, they would soon be confronted with the fact that such rules hamper the development of small improvements of the tests which nobody would like to miss.
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