Titlebook: Lupus; Molecular and Cellul Gary M. Kammer,George C. Tsokos Book 1999 Springer Science+Business Media New York 1999 Antigen.apoptosis.autoi

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f all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.978-1-4757-5686-9978-1-59259-703-1

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https://doi.org/10.1007/978-1-59259-703-1Antigen; apoptosis; autoimmunity; bacteria; cytokine; genetics; inflammation; lymphocytes; macrophages; patho

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Genetic Insights into Murine Lupus,tinguish” self antigens from nonself is the end result of an elaborate network of interrelated pathways that function to “tolerize” antiself B and T cells. Indeed, potentially autoreactive lymphocytes have been documented to be weeded out through a systematic array of B- and T-cell tolerance checkpoints (reviewed in refs. . and .).

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978-1-4757-5686-9Springer Science+Business Media New York 1999

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Contemporary Immunologyhttp://image.papertrans.cn/l/image/589127.jpg

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The Vascular Endothelium,es remain paramount in the pathogenesis of inflammation, the endothelial cell, once thought to be a passive bystander, is now recognized as one of the central, active participants in the inflammatory process. The endothelium dictates the site of inflammation and the types of cells involved in the in

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Nitric Oxide in Systemic Lupus Erythematosus, erythematosus (SLE) .. Although the inhibition of NO synthesis improves outcome in the MRL/. mice, the role of NO in the pathogenesis of SLE is as yet undetermined. The biology of NO, produced by constitutive or induced enzymes in virtually all tissues, is likely to exert complex actions on both im