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Titlebook: Lipoxygenases and their Metabolites; Biological Functions Santosh Nigam,Cecil R. Pace-Asciak Book 1999 The Editor(s) (if applicable) and Th

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書目名稱Lipoxygenases and their Metabolites
副標(biāo)題Biological Functions
編輯Santosh Nigam,Cecil R. Pace-Asciak
視頻videohttp://file.papertrans.cn/587/586925/586925.mp4
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Lipoxygenases and their Metabolites; Biological Functions Santosh Nigam,Cecil R. Pace-Asciak Book 1999 The Editor(s) (if applicable) and Th
描述This book is a result of the First Conference on Lipoxygenases, held at Malta, May 17th-2l st, 1997. The goal was very ambitious: having lipoxygenases as a focus for distant and diverse experimental approaches, we brought together scientists to discuss and build a consensus on the biological role of lipoxygenases. Although still fuzzy in many details, the Malta conference has shown that a unifying view on lipoxygenases is finally taking shape, and that the experimental evidence of links and conjugations among events OCCUf- ing from cell membranes to intracellular compartments and the nucleus is becoming in- creasingly convincing. The editors are deeply grateful to Hospital for Sick Children, Toronto, Free Univer- sity Berlin, NOAA Sea Grant College Program (U. S. A. ), Schering, Berlin (F. R. G. ), and Cayman Chemicals, Ann Arbor, Michigan (U. S. A. ), for their generous financial support, which was crucial in making the conference a scientific success. The conference received financial support from a number of additional sponsors, and we express our gratitude to Abbott Labs (U. S. A. ), Air Malta (Malta), Ass. Int. Cancer Res. (U. K. ), Biometra (F. R. G. ), Bayer AG (F. R. G. ),
出版日期Book 1999
關(guān)鍵詞biology; cancer; gene expression; inflammation; leukocyte; lipide; molecular biology; pathophysiology; pharm
版次1
doihttps://doi.org/10.1007/978-1-4615-4861-4
isbn_softcover978-1-4613-7205-9
isbn_ebook978-1-4615-4861-4Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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A 12(,)-Hete Receptor in Lewis Lung Carcinoma Cells, to histamine (5) . 12(.)-HETE also increases tumor cell adhesion to endothelium, subendothelial matrix and fibronectin (6). Moreover, it has recently been reported that 12(.)-HETE is an important regulator of cell survival and apoptosis by modulating the expression of bcl-2 protein (7).
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0065-2598 oxygenases as a focus for distant and diverse experimental approaches, we brought together scientists to discuss and build a consensus on the biological role of lipoxygenases. Although still fuzzy in many details, the Malta conference has shown that a unifying view on lipoxygenases is finally taking
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Aspirin-Triggered 15-Epi-Lipoxin A4 and Stable Analogs of Lipoxin A4 are Potent Inhibitors of Acute, and thus, in humans, LX are formed . during multicellular responses such as inflammation, atherosclerosis, and thrombosis (as reviewed in reference (1)). This branch of the eicosanoid cascade generates specific tetraene-containing products that appear to function as stop signals.
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Effect of 15-Hete on the 5-Lipoxygenase Pathway in Neutrophils,athway is controlled by a predominately antiinflammatory 15-lipoxygenase pathway.. The original observation of Vanderhoek and coworkers has been later confirmed by a number of investigators., however, no studies were performed to elucidate the precise mode of action of the inhibitory effect of 15-HETE. The aim of our study was to fill this gap.
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