Titlebook: Lactic Acid Bacteria: Genetics, Metabolism and Applications; Proceedings of the s R. J. Siezen,J. Kok,G. Schasfsma Conference proceedings 2

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The cell membrane and the struggle for life of lactic acid bacteriaive such conditions only for a short period of time. During periods of starvation LAB can exploit optimally the potential energy sources in their environment usually by applying proton motive force generating membrane transport systems. These systems include in addition to the proton translocating F

ineluctable

Erythropoietin

Global control of sugar metabolism: a Gram-positive solutionoordinate carbon source-specific regulation. This is achieved via carbon catabolite repression (CCR), which is the result of global transcriptional control and inducer exclusion. A common mechanism for transcriptional control has evolved within the group of low-GC Gram-positive bacteria, including l

negligence

Comparative genomics of phages and prophages in lactic acid bacterial bioinformatics tools. This technology, profiting from classical molecular-biology knowledge, has opened avenues of research for topics, which were difficult to address in the past. Now, it is possible to retrace part of the evolutionary history of phage modules by comparative genomics. The diagnos

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Gene regulation in ,: the gap between predicted and characterized regulatorsnome. It encodes 2310 proteins, and 138 of them were assigned as potential regulators, half of which being further classified by their similarity to known protein families. Among these regulators, most could have a direct role as transcriptional regulators, while the others may have less well define

osteoclasts

Transcriptome analysis and related databases of ,f . ssp. . IL1403. This will allow intraspecies comparative genomics studies as well as functional genomics studies aimed at a better understanding of physiological processes and regulatory networks operating in lactococci. This paper decribes the initial set-up of a DNA-microarray facility in our g

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considerable

Concomitant

Lantibiotics produced by lactic acid bacteria: structure, function and applicationsy of lactic acid bacteria. Based on their diverse structures and mode of action, at least six separate lantibiotic subgroups can be suggested, but all subgroups are characterized by significant post-translational modifications, which include the formation of (.-methyl)lanthionines, among other unusu