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Titlebook: Interleukin Protocols; Luke A. J. O’Neill,Andrew Bowie Book 2001 Humana Press 2001

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書目名稱Interleukin Protocols
編輯Luke A. J. O’Neill,Andrew Bowie
視頻videohttp://file.papertrans.cn/472/471137/471137.mp4
概述Includes supplementary material:
叢書名稱Methods in Molecular Medicine
圖書封面Titlebook: Interleukin Protocols;  Luke A. J. O’Neill,Andrew Bowie Book 2001 Humana Press 2001
描述Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and belong to a broader family termed cytokines. Collectively these proteins are the key orchestrators of host defense and the response to tissue injury. There are currently 23 different interleukins (numbered from IL-1 to IL-23), although the full extent of the interleukin family will only become clear upon analysis of the human genome sequence. Most important, interleukins are central to the pathogenesis of a wide range of diseases that involve an immune com- nent, including such conditions as rheumatoid arthritis, multiple sclerosis, ulcerative colitis, psoriasis, and asthma. Interleukins have also been imp- cated in other conditions, including cancer, migraine, myocardial infarction, and depression. In essence, when cells are activated by interleukins, a program of gene expression is initiated in the target cell that alters the cell’s phenotype, leading to enhanced immune reactivity, inflammation, and/or proliferation. Interleukins are therefore at the core of the cellular basis for many diseases. They are the subject of intense inve
出版日期Book 2001
版次1
doihttps://doi.org/10.1385/1592591469
isbn_softcover978-1-61737-162-2
isbn_ebook978-1-59259-146-6Series ISSN 1543-1894 Series E-ISSN 1940-6037
issn_series 1543-1894
copyrightHumana Press 2001
The information of publication is updating

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Isolation of Total and Bioactive Interleukins by Immunoaffinity-Receptor Affinity Chromatographyprocedure isolates the total amount of a specific cytokine, and the latter procedure isolates the bioactive fraction of the immunoaffinity-purified material. Recombinant receptors are becoming available for a number of different biologic materials and are available in forms suitable for affinity chromatography.
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Whole Blood Assays and the Influence of Circadian Rhythmicity on Human Cytokine Measurementmay lead to increased assay variation or, most importantly, an erroneous result. Circadian rhythms of immunologic relevance include variation in the number of circulating T cells (.), the autologous mixed lymphocyte reaction (.), the phagocytic index (.), and urinary neopterin secretion (.).
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ect covering various aspects of biology, soil science, and silviculture. The project was integrated as part of the Forest Ecosystem Team under the BIO-COSMOS Program funded by the Ministry of Agriculture, Forestry and Fisheries. As the coordinators of the Forest Ecosystem Team, we are pleased that r
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