Titlebook: Immunoreceptor Tyrosine-based Inhibition Motifs; Marc Da?ron,Eric Vivier Book 1999 The Editor(s) (if applicable) and The Author(s), under

逗留

Ebct207

HLA-Specific and Non-HLA-Specific Human NK Receptors,n that NK cells have the ability to kill “normal nonself” cells while sparing “normal self” cells expressing normal levels of MHC class I molecules and at least some allogeneic target cells expressing MHC class I molecules that are identical or related to the self ones (Karre 1992; Moretta et al. 19

Insufficient

Regulation of NK Cell Functions Through Interaction of the CD94/NKG2 Receptors with the Nonclassicaeptors belonging to the Ig superfamily can recognize groups of HLA class I molecules, such as two distinct groups of HLA-C alleles (KIR2DL1, KIR2DL2, KIR2DL3, KIR2DS1, KIR2DS2), one group of B alleles displaying Bw4 supertypic specificity (KIR3DL1), and the HLA-A alleles, HLA-A3 and HLA-A11 (KIR3DL2

falsehood

Graves’-disease

Paired Immunoglobulin-like Receptors of Activating and Inhibitory Types,noreceptor tyrosine-based inhibitory motif (ITIM), with the consensus sequence of I/V/L/S-x-Y-x-x-V/L, which is the focus of this volume, was originally described in the cytoplasmic tails of the low affinity Fc receptor for IgG antibodies (FcγRUB) on B cells and the killer inhibitory receptors (KIR)

搖晃

The Enigma of Activating Isoforms of ITIM-Bearing Molecules,SIRPα, (Kharitonenkov et al. 1997)]. All these molecules are characterized by the presence of one or more ITIM sequences in their intracytoplasmic portions. This motif is responsible for the transduction of inhibitory signals inside the cells. The ITIM-bearing receptors belong to two families: the i

BATE

jaunty

,Negative Regulation of Hematopoietic Cell Activation and Proliferation by FcγRIIB,G antibodies either complexed to multivalent soluble antigens or bound to cell membrane antigens. The FcγRIIB gene possesses three exons that encode the intracytoplasmic domain. By alternative splicing, it generates two (in humans) or three (in mice) isoforms of membrane FcγRIIB that differ only in

溫和女人

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