Titlebook: Immunoreceptor Tyrosine-based Inhibition Motifs; Marc Da?ron,Eric Vivier Book 1999 The Editor(s) (if applicable) and The Author(s), under

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978-3-642-63634-9The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE

Indigence

Infirm

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Current Topics in Microbiology and Immunologyhttp://image.papertrans.cn/i/image/462281.jpg

Aids209

Cantankerous

Interactions of LIRs, a Family of Immunoreceptors Expressed in Myeloid and Lymphoid Cells, with Viron usually occurs early in life with only mild and subclinical disease, followed by virus latency that can last for the lifetime of immunocompetent individuals. However, reactivation of the virus can occur in immuno-compromised patients, such as AIDS and transplant patients, and become a major cause of morbidity and mortality.

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LAIR-1, a Widely Distributed Human ITIM-Bearing Receptor on Hematopoietic Cells, the mechanisms underlying autoimmune disease. Here, a novel inhibitory receptor, LAIR-1, is discussed. LAIR-1 has a broad cellular distribution in the immune system and thus might play a role in the regulation of a variety of immune responses.