Titlebook: Immunological Aspects of Cancer; J. E. Castro Book 1978 MTP Press Limited 1978 cancer

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Human tumour-associated antigens: methods of , detection, of such entities in many experimental tumours, using assays of both cellular and humoral immunity.. It seems implausible that human tumours should be exceptional in this regard, although one might anticipate that the variability of antigen expression might be at least as great as that encountered a

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T Effector cells, realized, attempts at immunotherapy have provided sufficient encouragement for this goal to be pursued. Along the way, the complex nature of the response to tumours has become evident, although it is unclear which mechanisms are important in protection against spontaneous tumours in man.

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Macrophages and cancer,e has been the subject of many reviews and books., and is quite beyond the scope of this article. A brief survey only will be given, therefore, of the properties of macrophages in so far as they may relate to immunological and non-immunological host defence mechanisms against cancer. First it is nec

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Host immunity in experimental metastasis,rom cancer no matter what the modality of therapy, because of multiple tumour growth. Until cancer can be prevented, the goal of the clinician should be to prevent and/or treat distant tumour growths. The pathogenesis of metastasis is a complex biological phenomenon which depends on the interaction

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Immunodiagnosis,ur immunologists during the past 20 years (Table 12.1). The first of these has been the demonstration that many, if not all, tumour cells express constituents that are absent, or virtually absent, from corresponding normal cells. Since these cellular components have been sought and found by means of