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Titlebook: Immunological Aspects of Cancer; J. E. Castro Book 1978 MTP Press Limited 1978 cancer

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發(fā)表于 2025-3-21 17:46:51 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Immunological Aspects of Cancer
編輯J. E. Castro
視頻videohttp://file.papertrans.cn/463/462176/462176.mp4
圖書封面Titlebook: Immunological Aspects of Cancer;  J. E. Castro Book 1978 MTP Press Limited 1978 cancer
描述An immunological approach to the treatment of cancer has many theoretical features to commend it. There should be specificity, so that tumour cells alone are destroyed whilst normal tissues are unaffected. Provided the tumour is uni- form and all of the cells have appropriate antigens, every malignant cell should be destroyed and even distant metastases dealt with. So far these speculative advantages are unfulfilled and the initial optimism that surrounded im- munotherapy has not been sustained. Acceptance of the precepts of tumour im- munology continues but these disappointing observations had led to increasing scrutiny of certain aspects. The purpose of this chapter is to review the prin- ciples which underly tumour immunology and immunotherapy, so that the more detailed studies that follow can be considered in perspective. TUMOUR ANTIGENS (Chapter 2) For a tumour to initiate an immunological response, it must possess distinctive antigens. Much of the early work in tumour immunity was confused because it was not appreciated that tumours, like other tissues, exhibit transplan- tation antigens. Only when syngeneic tumours are used can tumour antigens alone be studied and it was the
出版日期Book 1978
關(guān)鍵詞cancer
版次1
doihttps://doi.org/10.1007/978-94-010-9418-4
isbn_softcover978-94-010-9420-7
isbn_ebook978-94-010-9418-4
copyrightMTP Press Limited 1978
The information of publication is updating

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Immunotherapy of leukaemia,sment of the results of such trials, but an attempt will also be made to assess the possible role of other forms of immunotherapy. Where possible, the current clinical trials will be placed into the perspective of what is known about specific immunity in haematological neoplasia and how immunotherapy can be measured ..
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Experimental specific immunotherapy,l adult tissue. (2) The host is often capable of an immune response against its malignant neoplasm. (3) Immune competence of the host is related, albeit imperfectly, to prognosis. (4) Immunological resistance to tumour growth can be effected.
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r cells alone are destroyed whilst normal tissues are unaffected. Provided the tumour is uni- form and all of the cells have appropriate antigens, every malignant cell should be destroyed and even distant metastases dealt with. So far these speculative advantages are unfulfilled and the initial opti
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Cancer: the product of abortive redifferentiation,f metazoan development. Much is known of the descriptive and morphological events of tissue differentiation, but practically nothing concrete is charted of the molecular events. Increasingly, the strong relationship between cancerous processes and developmental processes are being rediscovered.
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