Titlebook: Immune Checkpoint Blockade; Methods and Protocol Yago Pico de Coa?a Book 2019 Springer Science+Business Media, LLC, part of Springer Nature

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Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Chromium Release Assayc region of antibodies that at the same time bind specifically to cell surface antigens. ADCC stimulates the secretion of perforin, granzymes, and cytokines leading to lysis of the malignant cells. Natural killer (NK) cells express the CD16 receptor and can therefore be activated by ADCC to kill tum

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Establishment of Melanoma Tumor Xenograft Using Single Cell Line Suspension and Co-injection of Patim. The in vitro environment can lack the three-dimensional structure of the tumor, other cell types present within the tumor microenvironment, and important growth factors. Humanized mouse models allow researchers to study primary tumor cells in a more natural environment. With further development o

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ting original records into small groups of at least . elements and, therefore, preserving .-anonymity. Usually, in order to avoid information loss, when records are large, i.e., the number of attributes of the data set is large, this data set is split into smaller blocks of attributes and microaggre

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Claudia Wickenhauser,Daniel Bethmann,Zipei Feng,Shawn M. Jensen,Carmen Ballesteros-Merino,Chiara Mas. In this context, crowdsourcing (or crowd computing) is becoming a common solution to provide answers to complex problems by automatically coordinating the potential of machines and human beings working together. Several challenges still separate crowdsourcing from its generalized acceptance by ind