Titlebook: Hemostasis and Thrombosis; Thomas G. DeLoughery Book 2019Latest edition Springer Nature Switzerland AG 2019 Bleeding Disorders.Coagulation

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Tests of Hemostasis and Thrombosis,Testing of hemostasis is done for three reasons: to screen for coagulation disorders, to diagnose these disorders, and to monitor therapy. Tests of hemostasis and thrombosis are performed on nearly every patient in the hospital.

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Bleeding Disorders: A General Approach,Patients with bleeding disorders may present in a variety of ways. History is a key step as well as using basic screening tests. Often by these simple procedures, one can narrow the differential considerably.

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Hemophilia,Hemophilia A and B—lack of factors VIII and IX, respectively—are the most common forms of hemophilia. This chapter reviews the pathogenesis of hemophilia, diagnosis, and treatment including the use of desmopressin and factor concentrates.

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Liver and Renal Disease,This chapter discusses bleeding and thrombotic issues in patients with renal and liver disease. Causes, testing for, and management of both issues are discussed.

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Immune Thrombocytopenia,This chapter discusses immune thrombocytopenia. Diagnosis is discussed as well as acute therapy. Patients who fail initial therapy are offered three choices of therapy: splenectomy, thrombopoietin agonists, and rituximab. Evans syndrome and ITP in pregnancy are also discussed.

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