| 書目名稱 | Hemorrhagic Fever Viruses | | 副標(biāo)題 | Methods and Protocol | | 編輯 | Maria S. Salvato | | 視頻video | http://file.papertrans.cn/426/425613/425613.mp4 | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | This volume presents protocols that analyze and explore hemorrhagic fever viruses (HFV). This book is divided into 5 parts: Part I begins with an overview on predicting viral pandemics and then covers methods for surveillance, diagnosis, and classification of HFV. This includes an antibody capture method using Lassa virus antigens. Part II discusses structural studies and reverse genetics of HFV. The chapters in this part describe envelope glycoprotein membrane fusion studies, arenavirus nucleocapsid protein, and the use of virus-like-particles to study viral egress. Part III explores in vivo models of HFV infections, and contains chapters on murine, guinea pig, and primate models for HFV, and methods to obtain a subset of primary human liver cells that can be cultured long-term. Part IV looks into immune assays and vaccine production for HFV. The chapters in this section cover the attenuated vaccine for Argentine HFV, detecting virus-antibody immune complexes in secondary dengue infections, and DNA vaccination. Part V discusses host responses to viral hemorrhagic fever, and contains chapters on identifying host restrictions to Junín or Dengue infection, and a cell-culture method t | | 出版日期 | Book 2018 | | 關(guān)鍵詞 | HFV; Zoonotic pathogens; Vaccine development; Phenotype identification; Pathogenesis | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-6981-4 | | isbn_softcover | 978-1-4939-8358-2 | | isbn_ebook | 978-1-4939-6981-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2018 |
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