Titlebook: HIV Reservoirs; Methods and Protocol Guido Poli,Elisa Vicenzi,Fabio Romerio Book 2022 Springer Science+Business Media, LLC, part of Springe

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Human Monocyte-Derived Macrophages (MDM): Model 2 a substantial resistance to the cytopathic effects triggered by viral infection. This feature, in addition to their homeostatic self-renewal capacity, strongly support the hypothesis that macrophages could serve as an additional reservoir of persistently infected cells in individuals receiving comb

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Modeling HIV Latency in Astrocytes with the Human Neural Progenitor Cell Line HNSC.100cades, where it infects mainly microglial cells and astrocytes. Brain tissues from HIV-infected individuals have been shown to harbor HIV proviruses and to express early viral products with neurotoxic properties, like Tat. Egress of HIV from astrocytes to the periphery in animals further supports a

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Inexorable

Pde5-Inhibitors

More than a Gender Issue: Testis as a Distinctive HIV Reservoir and Its Implication for Viral EradicV reservoirs are found in several organs including lymph nodes, gut, and testes. In men, and as seen in brain and eyes, testes represent a distinctive organ characterized by an immune privilege, allowing the tolerance of spermatozoa which only develop after puberty, long after the establishment of s

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