Titlebook: Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain; Vladimir Parpura,Arne Schousboe,Alexei Verkhratsky Book 2014

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Excitotoxicity and Mitochondrial Dysfunction Underlie Age-Dependent Ischemic White Matter Injury,scavenge reactive oxygen species (ROS) in response to excitotoxicity to sustain axon function. Aging exacerbates mitochondrial fusion, leading to progressive alterations in mitochondrial dynamics and function, presumably to effectively buffer increased Ca. load and ROS production. Interestingly, the

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Kennzahlenbasierte Unternehmenssteuerung,ls in both glutamatergic and GABAergic neurons. Since the glutamate–glutamine cycle is an open cycle that actively interfaces with other pathways, the de novo synthesis of glutamine in astrocytes helps to maintain the operation of this cycle. The fine-tuned biochemical specialization of astrocytes a

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