Titlebook: Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain; Vladimir Parpura,Arne Schousboe,Alexei Verkhratsky Book 2014

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Regulated Exocytosis in Astrocytes is as Slow as the Metabolic Availability of Gliotransmitters: Forty involves vesicles, which play a key role in cell-to-cell signaling. On the one hand, vesicles determine the signaling potential by delivering various receptors and transporters to the plasma membrane by vesicular exocytosis. On the other hand, vesicles are used in astrocytes for the release of v

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Adenosine and Glutamate in Neuroglial Interaction: Implications for Circadian Disorders and Alcoholr neuronal activity in the brain and play an important role in the regulation of complex behavior. Astrocytes actively participate in synapse formation and brain information processing by releasing and uptaking glutamate, .-serine, adenosine 5′-triphosphate (ATP), and adenosine. In the central nervo

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Role of Astrocytes in Delayed Neuronal Death: GLT-1 and its Novel Regulation by MicroRNAs, of astrocyte protection is rapid removal of excess glutamate from synaptic sites by astrocytic plasma membrane glutamate transporters such as GLT-1/EAAT-2, reducing excitotoxicity. Astrocytic mitochondrial function is essential for normal GLT-1 function. Manipulating astrocytic mitochondrial and GL

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Pathological Potential of Astroglial Purinergic Receptors,f these neuropathologies in a beneficial or detrimental way. Nucleotides, e.g. adenosine 5′-triphosphate (ATP), released after acute or chronic neuronal injury, are important mediators of glial activation and astrogliosis..Acute injury may cause significant changes in ATP balance, resulting in (1) a

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青少年