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Titlebook: Genomic Instability and Immortality in Cancer; Enrico Mihich,Leland Hartwell Book 1997 Springer Science+Business Media New York 1997 DNA.M

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書目名稱Genomic Instability and Immortality in Cancer
編輯Enrico Mihich,Leland Hartwell
視頻videohttp://file.papertrans.cn/383/382899/382899.mp4
叢書名稱Pezcoller Foundation Symposia
圖書封面Titlebook: Genomic Instability and Immortality in Cancer;  Enrico Mihich,Leland Hartwell Book 1997 Springer Science+Business Media New York 1997 DNA.M
出版日期Book 1997
關(guān)鍵詞DNA; Mammalia; Telomere; apoptosis; cancer; cell; cell division; chromosome; esophagus; mortality; senescence;
版次1
doihttps://doi.org/10.1007/978-1-4615-5365-6
isbn_softcover978-1-4613-7448-0
isbn_ebook978-1-4615-5365-6
copyrightSpringer Science+Business Media New York 1997
The information of publication is updating

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Aneuploidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression,ics and, more recently, by chromosome painting and interphase cytogenetics using fluorescence in situ hybridization (12,13), appears simply too difficult to be set in a cause-effect relationship. An initial preneoplastic genetic event predisposing to more generalized disruption of the genome has bee
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p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and its Role in Cell Cls arrest late in G1 when p53 is active. In addition to G1 arrest, regulation by p53 of the other major cell cycle checkpoint, G2/M, has recently been reported in two different systems (Stewart ., 1995; Agarwal .., 1995).
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Regulation of Telomere Length in Mammalian Cells,ons would lead to a progressive loss of DNA. Mammalian telomerase activity was first identified in HeLa cell extracts which can add over sixty T.AG. repeats onto a T.AG. oligonucleotide . [5]. Mouse cell extracts were shown to add at most one or two T.AG. repeats onto a T.AG. oligonucleotide . sugge
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,Neoplastic Progression in Barrett’s Esophagus,d carcinomas in surgical specimens. Although the study of advanced cancers is useful for identifying genetic abnormalities that have accumulated in the cancer, the ability of this approach to determine the order in which genetic and other abnormalities develop during earlier stages of neoplastic pro
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