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Titlebook: Gene Vaccines; Josef Thalhamer,Richard Weiss,Sandra Scheiblhofer Book 2012 Springer-Verlag/Wien 2012 RNA and DNA vaccines.antigen-specific

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書目名稱Gene Vaccines
編輯Josef Thalhamer,Richard Weiss,Sandra Scheiblhofer
視頻videohttp://file.papertrans.cn/382/381999/381999.mp4
概述Only updated volume on gene vaccines focus on the most promising.Approaches towards gene vaccination.Approaches close to or already in clinical use objective comparison of different methods and protoc
圖書封面Titlebook: Gene Vaccines;  Josef Thalhamer,Richard Weiss,Sandra Scheiblhofer Book 2012 Springer-Verlag/Wien 2012 RNA and DNA vaccines.antigen-specific
描述The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance.The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.
出版日期Book 2012
關(guān)鍵詞RNA and DNA vaccines; antigen-specific; gene vaccines; immune response; vaccination; vaccines
版次1
doihttps://doi.org/10.1007/978-3-7091-0439-2
isbn_softcover978-3-7091-1929-7
isbn_ebook978-3-7091-0439-2
copyrightSpringer-Verlag/Wien 2012
The information of publication is updating

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Cytokine Genes as Molecular Adjuvants for DNA Vaccines,s, parasites, cancers, and autoimmune diseases. However the relatively low efficacy of DNA vaccinations in large animal species and humans has hindered their practical use as therapeutics. Therefore, there is an urgent need to improve protective responses generated by DNA vaccines. Among various imp
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Pharmaceutical Non-Viral Formulations for Gene Vaccines,ffort has been spared in order to make genetic vaccination feasible. Unfortunately, most approaches failed to convert the promising results from rodents to larger animals and human beings. To make such systems available for a global community, simple, safe and highly effective delivery systems are h
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Prime Boost Regimens for Enhancing Immunity: Magnitude, Quality of Mucosal and Systemic Gene Vaccins to mimic infection and induce immunological memory that has the potential to confer protection. The use of live attenuated viruses, “killed” viruses and recombinant viral proteins for vaccination are classical vaccine approaches that have successfully induced protective antibody and cell mediated
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