Titlebook: Gene Therapy for Autoimmune and Inflammatory Diseases; Yuti Chernajovsky,Paul D. Robbins Book 2010 Birkh?user Basel 2010 Arthritis.Autoimm

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Gene therapy for arthritis,lications. Issues concerning vectors, promoters and the therapeutic genes are discussed and ideal features for safe, non toxic, efficient and regulated gene expression proposed. Finally, the results from preclinical studies and six clinical trials performed in RA patients are described.

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GLOSS

,Gene therapy: Sj?gren’s syndrome,be effective in the disease. Animal studies have shown that treatment with immunomodulatory molecules like interleukin 10 or vasoactive intestinal peptide can influence salivary function positively while changing the local inflammatory environment. Future research will have to show whether this approach is feasible in humans.

Hemiparesis

cringe

interrogate

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https://doi.org/10.1007/b138427els, either through local gene delivery to the joint space or through systemic gene delivery for immune intervention. This chapter reviews how certain clinical applications of gene therapy would be beneficial for RA patients and discusses the roadblocks that need to be solved for future clinical app

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