Titlebook: Gadd45 Stress Sensor Genes; M. Raza Zaidi,Dan A. Liebermann Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), under

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Gadd45 in Neuronal Development, Function, and Injury, damage sensation and repair, genotoxic stress, neoplasia, and molecular epigenetics. The genes were originally identified in in vitro screens of irradiation- and interleukin-induced transcription and have since been implicated in a host of normal and aberrant central nervous system processes. These

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Advances in Architectural Geometry 2012tion during development. Gadd45 serves as an adaptor for DNA repair factors to promote removal of 5-methylcytosine from DNA at gene specific loci. Therefore, Gadd45 serves as a powerful link between DNA repair and epigenetic gene regulation.

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https://doi.org/10.1007/978-3-642-60612-0modulating cellular responses to senescence. Thus, exploring how Gadd45 proteins modulate cellular senescence has the potential to provide new and innovative tools to treat cancer as well as liver disease.

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