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Titlebook: Gadd45 Stress Sensor Genes; M. Raza Zaidi,Dan A. Liebermann Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), under

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發(fā)表于 2025-3-21 17:57:11 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Gadd45 Stress Sensor Genes
編輯M. Raza Zaidi,Dan A. Liebermann
視頻videohttp://file.papertrans.cn/381/380317/380317.mp4
概述Provides a comprehensive picture of the unique global role Gadd45 genes plays.Interest in Gadd45 stress signaling is exponentially increasing.Gadd45 stress signaling modulate a wide range of normal &
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Gadd45 Stress Sensor Genes;  M. Raza Zaidi,Dan A. Liebermann Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), under
描述.This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress.? It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors..The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins.? These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity.? Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation.. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45proteins play as stress sensors and the molecular pathways involved..
出版日期Book 2022Latest edition
關(guān)鍵詞gene function; proteins; stress sensors; stress signaling; cancer; innate immunity
版次2
doihttps://doi.org/10.1007/978-3-030-94804-7
isbn_softcover978-3-030-94806-1
isbn_ebook978-3-030-94804-7Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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發(fā)表于 2025-3-21 20:21:26 | 只看該作者
Gadd45 in Normal Hematopoiesis and Leukemia,d decreased apoptosis, and this was associated with hyper-activation of c-Jun NH2-terminal kinase and Stat5. Moreover, loss of Gadd45a also accelerated the development of BCR-ABL driven CML, and this was associated with enhanced PI3K-AKT-mTOR-4E-BP1 signaling, upregulation of p30C/EBPα expression, a
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發(fā)表于 2025-3-22 03:27:22 | 只看該作者
Gadd45 Proteins in Immunity 2.0,verview about Gadd45 proteins in the immune system, substantial progress has been made in our understanding of the immune system and with respect to Gadd45 proteins. Therefore, it is time for an update—Gadd45 proteins in immunity 2.0. In order to put Gadd45 proteins into the context of the immune sy
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發(fā)表于 2025-3-22 06:01:48 | 只看該作者
Gadd45 in the Liver: Signal Transduction and Transcriptional Mechanisms, activates its transcriptional stimulation. Thus, Gadd45β protects the liver through two entirely different processes: Binding MKK7 to block damaging signal transduction, or binding CAR to coactivate anabolic transcription.
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Architectural Acoustics for Practitioners,d decreased apoptosis, and this was associated with hyper-activation of c-Jun NH2-terminal kinase and Stat5. Moreover, loss of Gadd45a also accelerated the development of BCR-ABL driven CML, and this was associated with enhanced PI3K-AKT-mTOR-4E-BP1 signaling, upregulation of p30C/EBPα expression, a
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Advances in Artificial Intelligence activates its transcriptional stimulation. Thus, Gadd45β protects the liver through two entirely different processes: Binding MKK7 to block damaging signal transduction, or binding CAR to coactivate anabolic transcription.
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發(fā)表于 2025-3-23 05:33:49 | 只看該作者
0065-2598 tability, and inflammation.. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45proteins play as stress sensors and the molecular pathways involved..978-3-030-94806-1978-3-030-94804-7Series ISSN 0065-2598 Series E-ISSN 2214-8019
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